3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one
220904-83-6
520.9
C15H8Br2INO2
DMF, DMSO
-20°C
GW 5074 is a potent cRAF1 kinase inhibitor (IC = 9 nM). Shows 100-fold selectivity for Raf kinase versus Cdk1, Cdk2, c-src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms. cRAF1 inhibitors are predicted to be broad spectrum antitumor agents.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
